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KMID : 0388220140210060336
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Journal of the Korean Rheumatism Association
2014 Volume.21 No. 6 p.336 ~ p.339
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Hemorrhagic Cystitis with Giant Cells in Rheumatoid Arthritis Treating with Tacrolimus
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Min In-Suk
Ju Yeon-Mi
Kim Hyun-young
Choi Yun-Jung
Lee Won-Seok
Yoo Wan-Hee
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Abstract
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Hemorrhagic cystitis is a diffuse inflammation of the mu-cosa of the bladder, characterized by hematuria and burn-ing upon urination. This might be caused by a variety of reasons, including undergoing chemotherapy (such as cy-clophosphamide), radiation therapy, bladder cancer, cer-tain viruses, urinary infections, and thrombocytopenia. There are no previous reports of hemorrhagic cystitis asso-ciated with the use of tacrolimus. This is the first case of hemorrhagic cystitis due to tacrolimus for the treatment of rheumatoid arthritis. We describe a case of hemor-rhagic cystitis with giant cells in a patient with rheumatoid arthritis treating with tacrolimus. Hematuria resolved spontaneously with discontinuation of the drug.
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KEYWORD
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Hemorrhagic cystitis, Rheumatoid arthritis, Tacrolimus
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